Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep841 | Clinical case reports - Pituitary/Adrenal | ECE2017

Effect of the addition of lanreotide autogel to the treatment of an aggressive prolactinoma – a case report

Vilar Lucio , Vilar Clarice , Albuquerque Jose Luciano , Gadelha Patricia , The Ana Carolina , Trovao Erik , Cardoso Izabela , Cardoso Thaise , Lyra Ruy

Case report: A giant prolactinoma (size=5.2×4.1×3.2 cm; PRL=6 400 ng/mL) was diagnosed in an amenorrheic 19-year old girl who presented to the emergency room complaining of headaches and bilateral decrease in visual acuity for 10 days. The patient was started on cabergoline (CAB) in progressive doses up to 3 mg/week. PRL levels decreased from 6 400 to 4 600 ng/dl within 60 days, with improvement of visual complaints and visual fields defects. The dose was subsequentl...

ea0049ep975 | Pituitary - Clinical | ECE2017

The use of increasing doses of cabergoline in the management of cabergoline-resistant prolactinomas

Vilar Lucio , Vilar Clarice , Albuquerque Jose Luciano , Gadelha Patricia , The Ana Carolina , Trovao Erik , Borges Thaise , Cardoso Izabela , Lyra Ruy

Introduction: Dopamine agonists (DA) are the ideal treatment for prolactinomas and cabergoline (CAB) is the drug of choice, for being much more effective and better tolerated than bromocriptine. However, 10-15% of patients with prolactinomas are considered to be resistant to CAB, as they dot not achieve prolactin (PRL) normalization, while in use of conventional doses of this drug.Objective: To evaluate the effiaccy of increasing doses of CAB in prolacti...

ea0049ep899 | Neuroendocrinology | ECE2017

Endogenous Cushing’s syndrome ( clinical and biochemical features in a large cohort of patients

Vilar Lucio , Vilar Clarice , Albuquerque Jose Luciano , Trovao Erik , The Ana Carolina , Gadelha Patricia , Melo Maira , Gomes Barbara , Borges Thaise , Cardoso Izabela , Lyra Ruy

Patients and methods: We retrospectively analysed the clinical and biochemical characteristics of a cohort of 150 patients with endogenous Cushing’s syndrome (CS). Cushing’s disease (CD) accounted for 61.3% of cases (n=92), ectopic ACTH secretion (EAS) 7.3% (n=11), and adrenal diseases 31.3% (n=47). Among CD cases, there were 19 macroadenomas (20.6%), a female predominance (60.5%) and a median age of 33 years old (range 14–55). Bronchi...